TIMSS (Trends in Mathematics and Science Study) has conducted tests to determine and demonstrate students’ thinking skills profile, the result is a high level of students' ability to think in Indonesia is still low. Therefore Indonesia should try to improve students' thinking skills. One of the way to apply learning is to improve and stimulate students' thinking skills by appropiate learning models. A learning will be said meaningful (meaningful learning) if it is not boring and involves creating a student activity, so that students experience the learning. Typically meaningful learning is contextual and constructivism. Students are trained to build his own knowledge and brought into the real world of their everyday experience. Learning Problem-based learning (PBL) with the local culture science and science-based learning gives students the chance to learn the contextual and constructivism, and can make learning more meaningful (meaningful learning). This paper will discuss how PBL based local culture science which can make learning becomes meaningful.

Keyword : Problem-based learning, meaningful learning, local-culture science, learning model